John Isham1 
He lived Pytchley and Braunton.1
Child of John Isham and Anne Fitzwilliam
Elizabeth Dunch1
Her married name became Isham.
John Isham1 

by Gerlach Flicke 2
John Isham was born circa August 1525.1 He was the son of Euseby Isham and Anne Pulton.3 He married Elizabeth Barker, daughter of Nicholas Barker, on 6 October 1552.1 He died before 15 May 1596.1
He was a merchant adventurer at London, England.1 In 1559/60 they bought from Sir William Cecil the Manor and advowson of Lamport, with John later inheriting Robert’s share.1 He was He built Lamport Hall.1 He held the office of High Sheriff of Northamptonshire in 1581.1 He lived at Lamport Hall, Lamport, Northamptonshire, England.1
Child of John Isham and Elizabeth Barker
- Thomas Isham+3 b. 11 Sep 1555, d. 3 Dec 1605
Elizabeth Barker1
From 6 October 1552, her married name became Isham.
Child of Elizabeth Barker and John Isham
- Thomas Isham+2 b. 11 Sep 1555, d. 3 Dec 1605
Thomas Isham1 
Circa 1567 he became blind.1 He lived at Lamport Hall, Lamport, Northamptonshire, England.1
Children of Thomas Isham and Elizabeth Nicholson
- unknown daughter Isham1
- unknown daughter Isham1
- unknown daughter Isham1
- Sir John Isham, 1st Bt.+2 b. 27 Jul 1582, d. 8 Jul 1651
Christopher Nicholson1
Child of Christopher Nicholson
- Elizabeth Nicholson+2 d. 9 Aug 1621
Elizabeth Nicholson1 
From September 1576, her married name became Isham.
Children of Elizabeth Nicholson and Thomas Isham
- unknown daughter Isham1
- unknown daughter Isham1
- unknown daughter Isham1
- Sir John Isham, 1st Bt.+2 b. 27 Jul 1582, d. 8 Jul 1651
Sir John Isham, 1st Bt.1 
He was appointed Knight in 1608.1 He held the office of High Sheriff of Northamptonshire in 1611.1 He was created 1st Baronet Isham, of Lamport, co. Northampton [England] on 30 May 1627.1
Children of Sir John Isham, 1st Bt. and Judith Lewin
- unknown daughter Isham1
- unknown daughter Isham1
- Sir Justinian Isham, 2nd Bt.+2 b. 20 Jan 1610/11, d. 2 Mar 1675